Dataset On The Chemokine And Cytokine Responses Of Multi-Cell Cultures Treated With Porphyromonas Gingivalis Hemagglutinin B

Chemokines and cytokines produced in gingival tissues exposed to microorganisms and microbial products in dental plaque lead to local inflammation and tissue damage seen in periodontal disease. Bates et al. 2018 [1] reported that Porphyromonas gingivalis hemagglutinin B (HagB)-induced matrix metalloproteinase (MMP) responses of single cell cultures containing dendritic cells, gingival epithelial (GE) keratinocytes, or T cells were significantly different from the MMP responses of these same cells grown in multi-cell cultures. Here we report the concentrations (pg/ml) of HagB-induced IL1 alpha, IL6, IL8, IL12(p40), GM-CSF, MIP1 alpha MIP1 beta, RANTES, TNF alpha, and VEGF produced by dendritic cells, GE keratinocytes, or T cells in single cell cultures, two-cell cultures, or three-cell cultures. (C) 2019 The Authors. Published by Elsevier Inc.