Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock.

Margaret R Passmore,Nchafatso G Obonyo,Liam Byrne,Ai-Ching Boon,Sara D Diab,Kimble R Dunster,Yoke L Fung,Michelle M Spanevello,Mohd H Fauzi,Sanne E Pedersen,Gabriela Simonova,Chris M Anstey,Kiran Shekar,John-Paul Tung,Kathryn Maitland,John F Fraser

Thrombosis Research（2019）

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摘要

•Fluid resuscitation results in prolonged prothrombin time and aPTT.•Fluid resuscitation results in decreased levels of antithrombin and Protein C.•ROTEM clotting time and clot formation time are prolonged with fluid resuscitation.

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关键词

aPTT,AT,CFT,CT,CVP,DIC,Hb,Hct,LPS,MAP,MCF,PLT,PT,RCC,ROTEM,TEG,WCC

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