Reactive oxygen species modulate Na + -coupled neutral amino acid transporter 1 expression in piglet pulmonary arterial endothelial cells

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, pp. H911-H919, 2019.

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Abstract:

We have previously shown that Na+-coupled neutral amino acid transporter 1 (SNAT1) modulates nitric oxide (NO) production in pulmonary arterial endothelial cells (PAECs) from newborn piglets. Specifically, the ability to increase NO production in response to the L-arginine-NO precursor L-citrulline is dependent on SNAT1 expression. Elucid...More

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