Lung cancer therapy using doxorubicin and curcumin combination: Targeted prodrug based, pH sensitive nanomedicine

Yuan Hong,Shaomin Che,Beina Hui,Yunyi Yang,Xiaoli Wang,Xiaozhi Zhang,Yongqian Qiang,Hailin Ma

Biomedicine & Pharmacotherapy（2019）

引用 86|浏览3

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摘要

•U11 peptide conjugated, pH sensitive DOX prodrug (U11-DOX) was synthesized.•A CUR and U11-DOX co-encapsulated NPs system was constructed to treat lung cancer.•U11-DOX/CUR NPs have promising potential for combination treatment of lung cancer.

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关键词

Lung cancer,Urokinase plasminogen activator receptor,pH sensitive,Doxorubicin,Curcumin

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