RELEVANCE OF THE CYP2C19 POLYMORPHISM FOR LOADING AND MAINTENANCE DOSE OF PRASUGREL AND CLOPIDOGREL TREATMENT EFFECT IN CORONARY ARTERY DISEASE PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION PCI : THE PRAISE-GENE STUDY

Moo Hyun Kim,Long Zhe Guo,Eun-Seok Shin,Soe Hee Ann,Sun Young Choi,Young Seok Lee, Tae Hyung Kim

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2016）

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摘要

CYP2C19 polymorphism has been associated with altered antiplatelet potency of clopidogrel. On the other hand, prasugrel exerts greater and more consistent platelet inhibition with rapid onset when compared to clopidogrel in both healthy subjects and stable coronary artery disease patients. We sought

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