Mo1808 Infertility Care among Men and Women with Inflammatory Bowel Diseases in the CCFA Partners Cohort

at 1 year, 5 years, and 10 years and 15 years, respectively.Cumulative probabilities of perianal ulceration were 2%, 5%, 7% and 9% at 1 year, 5 years, 10 years and 15 years, respectively.No predictor of anal ulceration onset was observed.Conversely ileal disease at diagnosis was associated with less occurrence of anal ulceration (HR=0.53,IC95 [0.29-0.99]).Cumulative probabilities of fistulizing perianal Crohn's disease were 2%, 7%, 11% and 15% at 1 year, 5 years, and 10 years and 15 years, respectively.Perianal ulceration prior to anal fistula (HR=13.7, ) and rectal superficial and/or deep ulceration at diagnosis (HR=2,1, IC95 [1,2-3,65]) were predictors of fistulizing perianal disease onset.Anal stenosis was never observed without prior history of perianal lesion.Anal stenosis was describe in 13 patients (4%) concomitant to anal ulceration or following fistulizing perianal disease.Conclusions PCD are frequently observed during Crohn's disease for broadly one third of patient.These data underline the need to treat with effective treatment patient with rectal involvement of anal ulceration to avoid the onset of fistulizing perianal disease.