Access to 4,6-Diarylpicolinates via a Domino Reaction of Cyclic Sulfamidate Imines with Morita-Baylis-Hillman Acetates of Nitroolefins/Nitrodienes

Journal of Organic Chemistry, pp. 4378-4385, 2016.

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Abstract:

An interesting domino reaction of 5-membered cyclic sulfamidate imines with a variety of Morita–Baylis–Hillman acetates of nitroolefins/nitrodienes in the presence of DABCO as an organic base at 55 °C is reported for the first time. This new synthetic strategy provides a series of pharmacologically interesting 4,6-diarylpicolinates in hig...More

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