Delphinidin-rich extracts of Hibiscus sabdariffa L. trigger mitochondria-derived autophagy and necrosis through reactive oxygen species in human breast cancer cells

•Hibiscus anthocyanins induce autophagy and necrosis in human MCF-7 cells.•Hibiscus anthocyanins trigger autophagy via the AMP-activated kinase pathway.•Hibiscus anthocyanins stimulate reactive oxygen species generation.