GMP reductase and genetic uncoupling of adenylate and guanylate metabolism in Leishmania donovani parasites

Jan M. Boitz,Armando Jardim,Buddy Ullman

Molecular and Biochemical Parasitology（2016）

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摘要

The restricted growth phenotypes displayed by the Leishmania donovani Δgmpr and Δgmpr/Δimpdh null mutants confirms the importance of GMPR in the purine interconversion processes of this parasite.

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关键词

HGPRT,XPRT,dCF,ADSS,ASL,IMPDH,GMPR,CBS,PTS1,PHLEO,PAC,NEO,HYG,BSD,DME-L,G418

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