Optical Absorbance Sensitivity to Rugged Energy Landscape

Biophysical Journal, 2016.

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Abstract:

Previously we have shown that underdamped long-range intramolecular vibrations exist in proteins using anisotropic absorption in the terahertz frequency range [1,2]. Measurements on free chicken egg white lysozyme (CEWL) and CEWL bound to the inhibitor tri-acetylglucosamine (3NAG) found the anisotropic absorption dramatically changes with...More

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