Who Put the "A" in ATP? Generation of ATP from ADP-Ribose in the Nucleus for Hormone-Dependent Gene Regulation.

Molecular Cell(2016)

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摘要
In a recent issue of Science , Wright et al. (2016) describe a pathway for the synthesis of nuclear ATP, leading from NAD + to poly(ADP-ribose) to ADP-ribose to ATP, which supports the activity of ATP-dependent chromatin remodeling enzymes during hormone-dependent transcription.
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