NSE/S100-Neuromonitoring in Patients after Resuscitation and ECLS

Background: Neurological outcome is a limiting determinant after resuscitation. Recently, we reported increased serum neuron-specific enolase correlating with neuronal damage and increased mortality in patients after extracorporeal circuit-supported resuscitation. Using the time-course of serum NSE and S100 this analysis proves the usability of these biomarkers to indicate brain injury and mortality in patients after CPR/ECLS.