Ferulic acid-mediated protection against neomycin-induced hair cell loss in transgenic zebrafish

Journal of Functional Foods(2017)

引用 9|浏览4
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摘要
•FA is found in various fruits and vegetables, including citrus fruits, cabbage, and broccoli.•FA decreased neomycin-induced hair cell loss in dose-dependent and time-dependent manners.•FA has antioxidant effects and can prevent neomycin-induced apoptotic cell death in the hair cells.•Transgenic zebrafish may provide a useful model for preliminary ototoxic and otoprotective drug screenings.
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ao,hpf,dpf,FA,GFP,MI,O,OC,pvalb3,po,ROS,TUNEL
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