Hox Service Warranty Extends to Adult Bone Repair

Andrew J. Saurin,Marie-Claire Delfini,Yacine Graba

Developmental Cell（2016）

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摘要

Hox genes are key developmental regulators. In this issue of Developmental Cell , Rux et al. (2016) uncover an adult role for Hox11 genes in regionalized bone repair. This function relies on Hox activity in bone marrow multipotent mesenchymal stem progenitor cells, which promotes skeletal cell differentiation.

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