Pharmacological activation of the neurotensin receptor 1 abrogates the methamphetamine-induced striatal apoptosis in the mouse brain

Qingkun Liu, Ariela Hazan,Eddie Grinman,Jesus A. Angulo

Brain Research（2017）

引用 4|浏览3

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摘要

•Neurotensin receptor agonist PD149163 abrogates METH-induced apoptosis.•PD149163 protects from METH independent of hyperthermia.•PD149163 protects striatal neurons but not the dopamine terminals.•METH elevates striatal preproneurotensin mRNA levels.

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关键词

ip,METH,NPY,NTR1,PBS,PD149163,SOM

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