Genetic Testing Referral Patterns And Clinical Outcomes Among High-Risk Breast Cancer Survivors.

JOURNAL OF CLINICAL ONCOLOGY(2014)

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9589 Background: Referral patterns for genetic testing in breast cancer survivors are not well understood. We sought to identify a cohort of high-risk breast cancer survivors who had not been referred to understand patterns of referral and assess clinical outcomes. Methods: We identified breast cancer survivors (u003e 5 years) at MD Anderson who met at least one high-risk criteria and identified those who had not been referred for genetic counseling at our institution. Descriptive statistics were used to assess their characteristics and clinical outcomes. Results: We identified 5,941 high-risk breast cancer survivors, of whom 74% (N= 4,406) had not been referred for genetic counseling at our institution. The majority were female with a mean age at diagnosis of 43 years, and a median follow-up time of 116 months. Among those who had not been referred, 44% were initially diagnosed and treated at MD Anderson, whereas the rest were initially diagnosed and treated elsewhere. 52% were diagnosed prior to year 2000 a...
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