Complex Case of Methicillin Resistant Staphylococcus aureus Occipital Osteomyelitis and Subdural Empyema: Vancomycin or Linezolid?

Methicillin-resistant Staphylococcus aureus (MRSA) is typically considered a nosocomial pathogen, however it has now emerged to cause infections in the community. We report a case of MRSA bacteremia with subdural empyema and occipital osteomyelitis in a female with a history of significant intravenous drug use (IVDU). There are very few reports on MRSA bacteremia leading to problems with central nervous system (CNS) involvement.