Subcellular Electrode Arrays For Multisite Recording Of Dopamine In Vivo

Helen N. Schwerdt,Minjung Kim,Ekin Karasan,Satoko Amemori,Daigo Homma,Hideki Shimazu,Tomoko Yoshida,Robert Langer,Ann M. Graybiel,Michael J. Cima

30TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS 2017)（2017）

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摘要

We report the fabrication and use of carbon fiber (CF) arrays with 8 recording electrodes having individual diameters of 8 - 10 mu m (9 - 10 times smaller than conventional sensors and state of art) for electrochemical recording of dopamine from deep brain regions in a minimally invasive and high density manner. Accordingly, key advancements demonstrated are (1) radical reduction in size and (2) potential for wide spatial distribution of concurrent electrochemical measurement in the brain.

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关键词

subcellular electrode arrays,multisite recording,dopamine,carbon fiber arrays,electrodes,electrochemical recording,deep brain regions,radical size reduction,concurrent electrochemical measurement,size 8 mum to 10 mum

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