Surgical Staging And Its Prognostic Impact On Patients With Borderline Ovarian Tumors (Bot): A Subanalysis Of The Arbeitsgemeinschaft Gynaekologische Onkologie (Ago) Robot Study.

5562 Background: Incomplete surgical staging was shown to be a negative prognostic factor for patients with borderline ovarian tumors (BOT). However, little is known about the prognostic impact of each individual staging procedure. Methods: Clinical parameters of 950 patients with BOT (confirmed by central reference pathology) treated between 1998 and 2008 in 24 German AGO centers were analyzed. Staging quality was evaluated following German guidelines. In patients with adequate surgery regarding their reproductive organs (bilateral salpingo-oophorectomy or intended fertility preserving surgery in patients ≤55 years), other recommended staging procedures (omentectomy, peritoneal biopsies, cytology, and, for mucinous histology, appendectomy) were evaluated applying uni- and multivariate regression models with respect to progression-free survival (PFS), separately for serous and mucinous histology. Results: A total of 559 serous BOT (64.1%) were opposed to 268 mucinous BOT (30.7%). For patients with serous ...