Long noncoding RNA lncKdm2b is required for ILC3 maintenance by initiation of Zfp292 expression

Benyu Liu,Buqing Ye,Liuliu Yang,Xiaoxiao Zhu,Guanling Huang,Pingping Zhu,Ying Du,Jiayi Wu,Xiwen Qin,Runsheng Chen,Yong Tian,Zusen Fan

NATURE IMMUNOLOGY（2017）

引用 182|浏览147

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摘要

Long noncoding RNAs contribute to the cell-type-specific regulation of gene expression. Fan and colleagues identify a unique conserved lncRNA, lncKdm2b , that is transcribed divergently from the Kdm2b gene and is necessary for ILC3 maintenance in the gut.

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关键词

Chromatin remodelling,Innate lymphoid cells,Biomedicine,general,Immunology,Infectious Diseases

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