Multilayered co-electrospun scaffold containing silver sulfadiazine as a prophylactic against osteomyelitis: Characterization and biological in vitro evaluations

•The hybrid nanofiber was well-fabricated to different of two polymers using co-electrospun system.•The presence of silver sulfadiazine and silver ion release from the co-electrospun nanofiber was clearly proved.•The developed co-electrospun nanofiber showed not only excellent antibacterial effect, but also low cytotoxicity through in vitro tests.