Long-term treatment with eribulin in heavily pretreated women with metastatic breast cancer: a case series

Maria Morritti, Giuseppe Iodice, Assunta Melaccio,Loretta D’Onofrio,P. Bergnolo,Antonella Boglione,Alessandro Comandone, Peppina Molinaro, Danula Garigliano

FUTURE ONCOLOGY(2017)

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摘要
During the last decades, much effort has been made to develop and test treatments for advanced/metastatic breast cancer (MBC) able to prolong survival and improve patients' quality of life. In this regard, eribulin represents one of the most recent and interesting discoveries. This tubulin-targeting chemotherapy demonstrated a survival benefit in MBC women who progressed after at least two prior lines of chemotherapy for the treatment of metastatic disease (prior therapies should have included an anthracycline and a taxane, in either adjuvant or metastatic setting). Here, we described five cases of heavily pretreated MBC patients who experienced long-lasting control of disease with eribulin.
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关键词
chemotherapy,eribulin,line of treatment,metastatic breast cancer,progression-free survival
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