Construction and application of a model on the resolution of tropic acid enantiomers by enantioselective liquid-liquid extraction in centrifugal contactor separators

•Liquid-liquid extraction of TA enantiomers in centrifugal contactor separators is proposed.•Thermodynamics data about the physical partition coefficients and chemical equilibrium constants are obtained.•A multistage equilibrium model about the separation system is established.•Model predictions can predict the experimental process very well.•Purity and yield are significantly improved by changing the process parameters.