Long Term Outcomes Of Patients With Anaplastic Oligodendroglioma Treated In A Tertiary Care Centre In India.

e13517Background: Optimal management for anaplastic oligodendroglioma (ODG) is evolving through adjuvant radiation (RT) to adjuvant chemoradiation. We analyzed demography, treatment and survival outcome data of 56 patients of ODG registered in our institute from 2000 to 2013. Methods: All patients (Pts) underwent maximal safe surgical resection followed by adjuvant RT 60 Gy in 30 fractions. After 2004, pts underwent chemoradiation with daily Temozolomide TMZ) (75 mg/m2) and maintenance TMZ (150-200 mg/m2 D1-D5) for a total of six cycles. An event was described as death for overall survival, progression/ recurrence of disease, or neuro-deterioration for progression free survival. Log-rank test was used to compare event-free survival (EFS) distribution. Results: Median age at diagnosis was 38 years (range-19-77). 39 patients were male and 17 patients were female with a male: female ratio of 2.3:1. Headache was the commonest symptom seen in 56.4% patients followed by seizures (53.8%) and motor deficit (12.8%...