In vivo self-assembly induced retention of gold nanoparticles for enhanced photothermal tumor treatment

Xue-Feng Hu,Pei-Pei Yang,Jianping He,Ruijie Liang,Dechao Niu,Hao Wang,Yongsheng Li

JOURNAL OF MATERIALS CHEMISTRY B（2017）

引用 26|浏览8

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摘要

We present a simple route to fabricate peptide modified spherical gold nanoparticles (AuNPs@Pep1/Pep2) with enhanced retention performance in tumor sites for improved photothermal treatment (PTT), which was achieved through its in vivo self-assembly triggered by matrix metalloproteinase-2 (MMP-2).

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