Application of Amorphous Indium Gallium Zinc Oxide Thin Film Transistor Biosensors in Creatine Kinase Detection

Amorphous indium gallium zinc oxide (a-IGZO) thin film transistor (TFT) biosensors were fabricated by surface modification of the a-IGZO TFT devices and the immobilization of Creatine Kinase (CK-MM) antibodies on the a-IGZO TFT devices. When the fabricated CK-MM a-IGZO TFT biosensors were used to detect CK-MM in the sample, both the field effect mobility and the I-on/I-off ratio of the a-IGZO TFT devices were found to increase. These results indicate the potential applications for the developed a-IGZO TFT devices in biosensing. (c) 2017 The Authors. Published by Elsevier Ltd.