Two Cases of Hallopeau Type of Pemphigus Vegetans in Two Women in Burkina Faso

Jean-Baptiste Andonaba,Issouf Konaté, Konségré Valentin, Boukary Diallo, Muriel S Ouédraogo, Nina Néssiné Korsaga-Somé

Journal of Cosmetics, Dermatological Sciences and Applications(2017)

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摘要
Pemphigus of Hallopeau (PH) is a mild and pustular form of pemphigus vegetans,termed initially as “pyodermite vegetante” described by Hallopeau. Wereport cases in two black women. Two women aged 32 and 36 respectively(case 1 and case 2) were seen for a pustulosis associated with blisters and erosions.Their history and their review have found the mouth ulcerations. Theclinical examination showed pustules on the cephalic end, the trunk, the limbsand the large folds. Lesions had a polycyclic aspect and spread in a centrifugalway, developing towards budding, squamous and scabby erosions quicklysurrounded by new pustules. Regression left a pigmented macula. Histologicalexamination of the skin lesion showed images similar to vulgaris pemphigus(PV), together with hyperacanthosis and papillomatosis. Aspects observed inimmunofluorescence were identical to those of PV (case1). General corticoidtherapy led to a rapid disappearance of lesions in Case 1 but in Case 2 theLever protocol combining corticoid and methotrexate have been used. PH israrely described in our regions. Clinical diagnosis is not obvious for the uninitiated.Beyond the clinical presentation, PH has the same paraclinical diagnosisand the same treatment as PV.
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