CHEMGENIE: integration of chemogenomics data for applications in chemical biology

•Ongoing efforts at our company to integrate and structure chemogenomics data are described.•The usefulness of a chemogenomics database for common applications in drug discovery is highlighted.•Applications such as focused library design, model building and MoA deconvolution are shown.•Common caveats and pitfalls in capturing and interpreting chemogenomics data are discussed.