Effect of the co-exposure of benzo[a]pyrene with ethanol on the progression of fatty liver disease

TOXICOLOGY LETTERS(2017)

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摘要
The bacterial communication through signaling molecules termed quorum sensing has gained a lot of attention due to its applicability to different fields of study. Quorum sensing regulates several bacterial activities such as biofilm formation, antibiotic resistance, bioluminescence and bacterial virulence. These coordinated activities are only realized when the bacterial population reaches a high population density. The signaling molecules used in quorum sensing occur at very low concentrations which call for very sensitive methods for their identification and characterization. Many studies have been performed on the use of inhibitors in attempt to disrupt quorum sensing and consequently alleviate its negative effects. This article gives a description of the types of auto-inducers involved in quorum sensing and the fields of study they greatly affect especially the environmental one. It also covers types of analytical sample preparation and detection methods, and different types of inhibitors used for quorum quenching.
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关键词
fatty liver disease,fatty liver,ethanol,co-exposure
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