P1.02-063 Tumor Heterogeneity Analyzes by Integrated Proteo-Genomics of Thoracic Tumors from Sequential Biopsies and Warm Autopsies

Tumor heterogeneity modulates treatment response to targeted therapy. Both intra-tumor and inter-tumor heterogeneity is well characterized in various cancers, including lung cancer, the commonest cause of cancer death in both men and women. Tumor heterogeneity studies have been conducted mostly for early stage lung cancer. Furthermore, these studies have focused primarily on next-generation sequencing (NGS).