P3.02-089 Establishment of Highly Metastatic Lung Cancer Cell Sublines in Long-term Three-dimensional Low Attachment Cultures
JOURNAL OF THORACIC ONCOLOGY(2017)
摘要
Previous studies demonstrated that lung cancer with floating cell clusters in histology is more likely to develop metastasis. We investigated whether cancer cells in long-term, three-dimensional low attachment cultures acquire high metastatic potential and examined the mechanisms underlying metastasis.
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关键词
Metastasis model,epithelial-mesenchymal transition,Three-dimensional low attachment culture
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