Facile Synthesis of ZnO-Cu 2 O Composite Nanoparticles and Effect of Cu 2 O Doping in ZnO on Antimicrobial Activity

Modern Chemistry & Applications(2017)

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摘要
The comparative antibacterial activity of ZnO and ZnO-Cu2O composite nanoparticles has been investigated and presented in this manuscript. The present study describes the facile synthesis of pristine ZnO nanoparticles and ZnO-Cu2O composite nanoparticles respectively. ZnO nanoparticles and ZnO-Cu2O composite nanoparticles have been synthesized by simple solution process using zinc nitrate hexahydrate and copper acetate as sole precursor. The diameter of each ZnO and ZnO-Cu2O composite nanoparticles lies between 200 to 600 nm respectively as observed from SEM images. Herein, we scrutinized the influence of Cu2O doping in ZnO on the antibacterial activity. The E. coli bacteria which are generally ever-present have been chosen as the model organisms for relative study. The experimental procedures for the antibacterial test include spectroscopic method, taking different concentrations (10–40 μg/ml) of samples to unearth the minimum inhibitory concentration. Our analysis says that the minimum concentration of ZnO and ZnO-Cu2O composite nanoparticles which inhibited the growth of E. coli bacteria was found to be 10 μg. A mechanism was also proposed to describe the better antibacterial activity of the ZnO-Cu2O composite nanoparticles than the pure ZnO nanoparticles.
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