Secondary Metabolites of Hypericum L. Species as Xanthine Oxidase Inhibitors
Acta Facultatis Medicae Naissensis(2017)
摘要
Nine Hypericum species (H. barbatum, H. hirsutum, H. linarioides, H. olympicum, H. perforatum, H. rochelii, H. rumeliacum, H. tetrapterum and H. umbellatum) collected in Serbia were assayed for inhibitory potential against xanthine oxidase in vitro, on the commercial enzyme, and compared with allopurinol. Seven studied Hypericum species (H. barbatum, H. rochelii, H. rumeliacum, H. umbellatum, H. perforatum, H. tetrapterum and H. olympicum) inhibit commercial xanthine oxidase with an IC50 below 100 mu g/mL. H. barbatum exerted the most potent inhibitory effect (IC50 = 31.84 +/- 6.64 mu g/mL), followed closely by H. perforatum (IC50 = 37.12 +/- 4.06 mu g/mL).
更多查看译文
关键词
xanthine oxidase inhibition,Hypericum,secondary metabolites
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要