DETECTION OF FAMILIAL HYPERCHOLESTEROLEMIA IN SOUTH AFRICA VIA CASCADE SCREENING: THE WITS FIND-FH PROGRAM

Frederick J. Raal,Belinda A. Stevens, Raulene du Toit, Dominick Troendle,Gillian J. Pilcher, Matthew Kelso, Traci Turner,Evan A. Stein

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2018）

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摘要

Familial hypercholesterolemia (FH) is a major contributor to premature cardiovascular disease in South Africans of Afrikaner, Jewish and Indian descent due to gene founder effects. However, no systematic program exists to detect these families. Additionally, information regarding prevalence of FH in

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