Implantation of Electrospun Vascular Grafts with Optimized Structure in a Rat Model

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2018.

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Abstract:

Here, we present a protocol to fabricate macroporous PCL vascular graft and describe an evaluation protocol by using a rat model of abdominal aorta replacement. The electrospun vascular grafts often possess relatively small pores, which limit cell infiltration into the grafts and hinder the regeneration and remodeling of the neo-arteries....More

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