De novo Gene Signature Identification from Single-Cell RNA-Seq with Hierarchical Poisson Factorization

bioRxiv, pp. 367003-22, 2018.

Cited by: 1|Views33

Abstract:

Common approaches to gene signature discovery in single cell RNA-sequencing (scRNA-seq) depend upon predefined structures like clusters or pseudo-temporal order, require prior normalization, or do not account for the sparsity of single cell data. We present single cell Hierarchical Poisson Factorization (scHPF), a Bayesian factorization ...More

Code:

Data:

Full Text
Bibtex
Your rating :
0

 

Tags
Comments