Efficacy, biocompatibility, and clinical performance of a novel contact lens packaging solution additive designed to reduce handling-related bacterial contamination

Purpose: The hands are a potential source of lens bacterial contamination during blister pack removal and insertion. In an effort to reduce such contamination, the effect of a packaging solution containing e-poly-l-lysine (e-PL – a natural, biologically derived compound) on lens contamination by known ocular isolates was evaluated. Biocompatibility testing of e-PL packaged lenses was conducted to characterize safety. Furthermore, lenses were evaluated clinically for anterior ocular health, comfort, and fit.