2-Amino-6-chloropurine-modified Polyamidoamine-Mediated P53 Gene Transfection to Achieve Anti-Tumor Efficacy

Haobo Han,Wenqi Chen,Jiebing Yang,Jiayuan Zhang,Quanshun Li,Yan Yang

New journal of chemistry（2018）

引用 5|浏览15

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摘要

The modification of 2-amino-6-chloropurine on polyamidoamine was performed to synthesize a derivative, AP-PAMAM, which was then employed as a carrier for p53 gene delivery to achieve anti-tumor efficacy.

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