Genome-wide analyses and functional profiling of human NK cell lines

Justin T. Gunesch,Laura S. Angelo, Sanjana Mahapatra,Raquel P. Deering,Johanna E. Kowalko,Patrick Sleiman,John W. Tobias,Linda Monaco-Shawver,Jordan S. Orange,Emily M. Mace

Molecular Immunology（2019）

引用 27|浏览8

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摘要

•Found 557 genes with >50-fold difference in expression between at least 2 cell lines.•NK92 cells have a CD56bright-like phenotype while YTS cells are CD56dim-like.•Identified 417 genes differentially expressed between lytic and less lytic cell lines.

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关键词

NK cell,Cell line,Cytotoxicity,CD56,NK cell phenotype

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