GW29-e1697 Activation of Farnesoid X Receptor Enhances the Survival of Engrafted Adipose-Derived Mesenchymal Stem Cells in Mouse Post-Mi Heart

Wenjun Yan,Yunlong Xia,Fuyang Zhang,Yongzhen Guo,Yanjie Guo,Yuan He,Yi Liu,Rutao Wang,Tao Yin,Erhe Gao,Xinliang Ma,Ling Tao

Journal of the American College of Cardiology（2018）

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摘要

The poor survival of engrafted stem cells in the ischemic environment limits their therapeutic efficacy for myocardial infarction (MI) treatment. Previously, we demonstrated that GW4064, an farnesoid X receptor (FXR) agonist, ameliorated post-MI cardiac dysfunction and remodeling. The current study

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