Clinical Use of a Prediction Rule to Guide Admission Policy in Community-Acquired Invasive Urinary Tract Infection: A Randomized Clinical Trial

A total of 370 patients were included, 237 in the control period and 133 in the intervention period. Use of PRACTICE significantly reduced the primary hospitalization rate (from 92%, in the control group to 72%, in the intervention group, p <0.01). The secondary hospital admission rate after initial outpatient treatment was 6% in control patients and 27% in intervention patients (1/17 and 10/37; p<0.001). In none of these secondary admissions intensive care treatment was required, and no complications were noted. Introduction