An Opsonophagocytic Assay to Evaluate Immunogenicity of Non-Typhoidal Salmonella Vaccines.
CLINICAL AND VACCINE IMMUNOLOGY(2016)
摘要
Nontyphoidal Salmonella (NTS) invasive infections are an important cause of morbidity and mortality in sub-Saharan Africa. Several vaccines are in development to prevent these infections. We describe an NTS opsonophagocytic killing assay that uses HL-60 cells and baby rabbit complement to quantify functional antibodies elicited by candidate NTS vaccines.
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关键词
opsonophagocytic assay,immunogenicity
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