Giant variant of acquired perforating dermatosis in a renal dialysis patient.

Perforating dermatosis is a heterogeneous group of disorders characterized by transepidermal elimination of dermal components such as collagen, elastin, or fibrin. Acquired perforating dermatosis usually develops in adulthood in association with comorbid disease such as diabetes mellitus (DM) or renal failure. We present a diffuse and giant variant with an elastic fiber predominant elimination pattern, which has rarely been described.