Pregnancy Period and Early-Life Risk Factors for Inflammatory Bowel Disease: a Northern Finland Birth Cohort 1966 Study

Timo M. Blomster,Olli-Pekka Koivurova,Ritva Koskela,Karl-Heinz Herzig,Nicholas J. Talley,Jukka Ronkainen

BMC Public Health（2024）

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Abstract

The pathogenesis of inflammatory bowel disease (IBD) has not been fully elucidated. The aim of this study was to analyze the pregnancy period, perinatal period, and infancy period risk factors for IBD in a well-characterized birth cohort from Northern Finland. The Northern Finland Birth Cohort 1966 (NFBC1966) population comprises mothers living in the two northernmost provinces of Finland, Oulu, and Lapland, with dates of delivery between Jan 1st and Dec 31st, 1966 (12 055 mothers, 12 058 live-born children, 96.3

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Key words

Cohort studies,Crohn’s disease,Early life,Epidemiology,Inflammatory bowel diseases,Smoking,Ulcerative colitis

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