The multi-dimensional roles of astrocytes in ALS.

Neuroscience Research（2018）

引用 140|浏览14

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摘要

•Neurodegeneration in ALS is partly mediated by non-cell autonomous mechanism.•Astrocytes in ALS lose neuroprotective property and acquire toxic phenotypes.•Astrocytes are a viable therapeutic target for ALS.

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关键词

Astrocyte,Neuroinflammation,ALS,TDP-43,SOD1

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