Omega-3 Fatty Acids Reduce Inflammation in Rat Apical Periodontitis.

Mariane Maffei Azuma,João Eduardo Gomes-Filho,Edilson Ervolino,Carolina de Barros Moraes Cardoso,Camila Barbosa Pipa,Toshihisa Kawai,Leticia Citelli Conti,Luciano Tavares Angelo Cintra

Journal of Endodontics（2018）

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摘要

•The effects of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) on inflammatory mediators in apical periodontitis are discussed.•ω-3 PUFAs decreased the expression of tumor necrosis factor alpha, interleukin (IL)-6, IL-1β, and IL-17 in periapical tissues.•ω-3 PUFAs increased the expression of IL-10 in periapical tissues.

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关键词

Apical periodontitis,cytokine, endodontic infection,omega-3 fatty acid

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