Preclinical immunogenicity and safety of the cGMP-grade placental malaria vaccine PRIMVAC.

EBioMedicine(2019)

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摘要
This work paved the way for the clinical development of an easily scalable low cost effective vaccine that could protect against placental malaria and prevent an estimated 10,000 maternal and 200,000 infant deaths annually. FUND: This work was supported by a grant from the Bundesministerium für Bildung und Forschung (BMBF), Germany through Kreditanstalt für Wiederaufbau (KfW) (Reference No: 202060457) and through funding from Irish Aid, Department of Foreign Affairs and Trade, Ireland.
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关键词
Malaria,Plasmodium,Vaccine,VAR2CSA,Placenta
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