Donor-derived CIK Cell Infusion as Consolidation after Non-myeloablative Allogeneic Transplant for Myeloid Neoplasms.

Rupa Narayan,Jonathan E Benjamin,Omid Shah,Lu Tian, Keri Tate,Randall Armstrong,Bryan J Xie,Robert Lowsky,Ginna Laport,Robert S Negrin,Everett H Meyer

Biology of Blood and Marrow Transplantation（2019）

引用 13|浏览21

暂无评分

摘要

•We report a phase II study of cytokine-induced killer (CIK) cell therapy after total lymphoid irradiation and antithymocyte globulin conditioning for myeloid neoplasms.•Donor-derived CIK cells were produced from both related and unrelated donors.•A one-time CIK cell infusion as early post-transplant consolidation was safe.•Early donor chimerism and relapse/survival rates were similar to historical rates.

查看译文

关键词

Cytokine-induced killer cells,Non-myeloablative conditioning transplantation,Reduced-intensity conditioning transplantation,Myelodysplastic syndrome,Acute myeloid leukemia,Cell therapy

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要