Elimination of Ghost Peaks by Optimization of Anion Exchange Chromatography Method for Determination of Gamma-Carboxyglutamic Acid (Gla)-Domainless Impurity in Recombinant Activated Clotting Factor VII Drug Products.

Hamed Tahmasbi,Nahid Zarezadeh, Somaie Marjaninia, Behnaz Molavi,Shayan Maleknia,Fereidoun Mahboudi,Hossein Behrouz

Journal of Pharmaceutical and Biomedical Analysis（2019）

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Key words

Recombinant activated clotting factor VII activated (rFVIIa),Gamma-carboxyglutamic acid (Gla)-domainless,Strong anion Exchange,Tris Bis Tris propane,Ghost peaks

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