A Probabilistic Model of the Germinal Center Reaction

FRONTIERS IN IMMUNOLOGY, pp. 6892019.

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Abstract:

Germinal centers (GCs) are specialized compartments within the secondary lymphoid organs, where B cells proliferate, differentiate, and mutate their antibody genes. Upon exit from the GC, B cells terminally differentiate into plasma cells or memory B cells. While we have a good comprehension of plasma cell differentiation, memory B cell d...More

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